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ABP 688 is a high affinity human mGlu5 receptor antagonist (Ki = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM).
| Molecular Weight | 240.3 |
| Formula | C15H16N2O |
| CAS Number | 924298-51-1 |
| Solubility (25°C) | 1eq. HCl 12.02 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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