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Abelacimab

Cat. No. M24919

All AbMole products are for research use only, cannot be used for human consumption.

Abelacimab Structure
Synonym:

MAA868

Size Price Availability Quantity
100ug USD 175  USD175 In stock
1mg USD 350  USD350 In stock
5mg USD 950  USD950 In stock
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Quality Control & Documentation
Biological Activity

Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies.

Chemical Information
CAS Number 2098724-83-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Benjamin D Gallagher. N Engl J Med. Abelacimab for Prevention of Venous Thromboembolism

[2] Sudhamshi Toom, et al. N Engl J Med. Abelacimab for Prevention of Venous Thromboembolism

[3] Xiang Wang. N Engl J Med. Abelacimab for Prevention of Venous Thromboembolism

[4] B Alexander Yi, et al. J Thromb Haemost. Pharmacokinetics and pharmacodynamics of Abelacimab (MAA868), a novel dual inhibitor of Factor XI and Factor XIa

[5] Peter Verhamme, et al. N Engl J Med. Abelacimab for Prevention of Venous Thromboembolism

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Keywords: Abelacimab, MAA868 supplier, Factor Xa, inhibitors, activators

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