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6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme.
Molecular Weight | 302.24 |
Formula | C15H10O7 |
CAS Number | 4324-55-4 |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Hong Gao et al. Molecules. Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase
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