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6-Hydroxydopamine hydrochloride

Cat. No. M7832
6-Hydroxydopamine hydrochloride Structure
Synonym:

6-Hydroxydopamine hydrochloride; 6-OHDA hydrochloride

Size Price Availability Quantity
5mg USD 45  USD50 In stock
10mg USD 81  USD90 In stock
50mg USD 189  USD210 In stock
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Quality Control
Biological Activity

6-Hydroxydopamine hydrochloride is an antagonist of the neurotransmitter dopamine.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 205.64
Formula (HO)3C6H2CH2CH2NH2.HCl
CAS Number 28094-15-7
Purity >97%
Solubility Water: ≥50 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: 6-Hydroxydopamine hydrochloride, 6-Hydroxydopamine hydrochloride; 6-OHDA hydrochloride supplier, Dopamine Receptor, inhibitors

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