Free shipping on all orders over $ 500

6-Aminofluorescein

Cat. No. M25380
6-Aminofluorescein Structure
Synonym:

6-AF

Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

6-Aminofluorescein (6-AF) is a novel fluorescent dye.

Chemical Information
Molecular Weight 347.32
Formula C20H13NO5
CAS Number 51649-83-3
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Gahininath Y Bharate, et al. J Pers Med. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging

[2] Suman Basak, et al. Nanoscale Adv. Nanoconfined anti-oxidizing RAFT nitroxide radical polymer for reduction of low-density lipoprotein oxidation and foam cell formation

[3] Matthias Hartlieb, et al. J Mater Chem B. Core cross-linked nanogels based on the self-assembly of double hydrophilic poly(2-oxazoline) block copolymers

[4] Sarah A Richardson, et al. Macromol Biosci. Covalent Attachment of Fibronectin onto Emulsion-Templated Porous Polymer Scaffolds Enhances Human Endometrial Stromal Cell Adhesion, Infiltration, and Function

[5] R M McKinney, et al. J Chem Soc Perkin 1. Reaction paths to pure 5- and 6-aminofluorescein. Pitfalls encountered in conventional synthesis procedures

Related Fluorescent Dye Products
FM1-43

FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.

BCIP

BCIP is a chromogenic substrate for colorimetric assay of alkaline phosphatase activity.

MCA-SEVNLDAEFR-K(Dnp)-RR, amide

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.

MeOSuc-AAPV-AMC

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).

Enhanced Green Fluorescent Protein (EGFP) (200-208)

Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria.

  Catalog
Abmole Inhibitor Catalog




Keywords: 6-Aminofluorescein, 6-AF supplier, Fluorescent Dye, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.