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5-Fluoro-2′-deoxycytidine

Cat. No. M7804

All AbMole products are for research use only, cannot be used for human consumption.

5-Fluoro-2′-deoxycytidine Structure
Size Price Availability Quantity
5mg USD 55  USD55 In stock
10mg USD 100  USD100 In stock
25mg USD 210  USD210 In stock
50mg USD 360  USD360 In stock
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Quality Control & Documentation
Biological Activity

5-Fluoro-2′-deoxycytidine is a mechanism based DNMT (DNA cytosine-5 methyltransferase) inhibitor, that forms a covalent link with the cysteine residue in the active site of DNMT.

Chemical Information
Molecular Weight 245.21
Formula C9H12FN3O4
CAS Number 10356-76-0
Solubility (25°C) DMSO: ≥20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Andrei Solodinin, et al. 5-Fluoro-2'-deoxycytidine as a Probe for the Study of B/Z-DNA Transition by 19 F NMR Spectroscopy

[2] Hung-Man Yu, et al. Evaluation of 5-[ 18 F]fluoro-2'-deoxycytidine as a tumor imaging agent: A comparison of [ 18 F]FdUrd, [ 18 F]FLT and [ 18 F]FDG

[3] Marie Morfouace, et al. Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors

[4] Duoli Guo, et al. Stability of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in combination

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Keywords: 5-Fluoro-2′-deoxycytidine supplier, inhibitors, activators

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