Free shipping on all orders over $ 500

4-Methylumbelliferyl α-D-galactopyranoside

Cat. No. M10264
4-Methylumbelliferyl α-D-galactopyranoside Structure
Synonym:

4MU-α-Gal

Size Price Availability Quantity
50mg USD 120  USD120 In stock
100mg USD 200  USD200 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

4-Methylumbelliferyl α-D-galactopyranoside is a blue pro-fluorogenic substrate.

Chemical Information
Molecular Weight 338.31
Formula C16H18O8
CAS Number 38597-12-5
Solubility (25°C) DMSO ≥ 30 mg/mL (Need ultrasonic)
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ronald K Gary, et al. Anal Biochem. Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts

[2] M I Khan, et al. Eur J Biochem. Fluorescence polarization as a tool to study lectin-sugar interaction. An investigation of the binding of 4-methylumbelliferyl beta-D-galactopyranoside to Abrus precatorious agglutinin

[3] M I Khan, et al. Eur J Biochem. Binding of 4-methylumbelliferyl beta-D-galactopyranoside to Momordica charantia lectin: fluorescence-quenching studies

[4] M I Khan, et al. Biochem J. Fluorescence-polarization studies on binding of 4-methylumbelliferyl beta-D-galactopyranoside to Ricinus communis (castor-bean) agglutinin

[5] D Mitra, et al. Biochem J. Physicochemical studies of binding of 4-methylumbelliferyl beta-D-galactopyranoside to cold agglutinin

Related Fluorescent Dye Products
SOSG

SOSG (Singlet Oxygen Sensor Green Fluorescent Probe) is highly selective for singlet oxygen (1O2). It is commonly used for the detection of singlet oxygen in solutions and the evaluation of the efficacy of free radical scavengers.

FM1-43

FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.

BCIP

BCIP is a chromogenic substrate for colorimetric assay of alkaline phosphatase activity.

MCA-SEVNLDAEFR-K(Dnp)-RR, amide

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.

MeOSuc-AAPV-AMC

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).

  Catalog
Abmole Inhibitor Catalog




Keywords: 4-Methylumbelliferyl α-D-galactopyranoside, 4MU-α-Gal supplier, Fluorescent Dye, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.