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3-(3-Hydroxybutyl)phenol

Cat. No. M17144
3-(3-Hydroxybutyl)phenol Structure
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Biological Activity

3-(3-Hydroxybutyl)phenol (Oil)

Chemical Information
CAS Number 854464-95-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Olorunfemi A Eseyin, et al. Nat Prod Res. Phytochemical analysis and antioxidant activity of the seed of Telfairia occidentalis Hook (Cucurbitaceae)

[2] Fang Luo, et al. Sci Total Environ. Characterization of bimetallic Fe/Pd nanoparticles by grape leaf aqueous extract and identification of active biomolecules involved in the synthesis

[3] Kei Shimoda, et al. Phytochemistry. Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana

[4] Lang-Ping Dong, et al. Chem Biodivers. Four new compounds from the leaves of Acer truncatum

[5] M Tahara, et al. J Antibiot (Tokyo). Resorthiomycin, a novel antitumor antibiotic. II. Physico-chemical properties and structure elucidation

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