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2-NBDG

Cat. No. M6327

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2-NBDG Structure
Size Price Availability Quantity
1mg USD 100  USD100 In stock
5mg USD 300  USD300 In stock
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Biological Activity

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. 

Product Citations
Chemical Information
Molecular Weight 342.26
Formula C12H14N4O8
CAS Number 186689-07-6
Form Solid
Solubility (25°C) DMSO 14 mg/mL
Storage -20°C, protect from light
References

[1] Jaewoo Hong, et al. Int J Mol Sci. The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1α and Glut-1 Expression and Glucose Uptake in the Brain

[2] Yuanyuan Zhu, et al. Cell Mol Neurobiol. Single-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes

[3] Rahul Pal, et al. Sci Rep. In-vivo topical mucosal delivery of a fluorescent deoxy-glucose delineates neoplasia from normal in a preclinical model of oral epithelial neoplasia

[4] Masturah Bte Mohd Abdul Rashid, et al. J Lab Autom. Identification and Optimization of Combinatorial Glucose Metabolism Inhibitors in Hepatocellular Carcinomas

[5] Chenhui Zou, et al. J Biochem Biophys Methods. 2-NBDG as a Fluorescent Indicator for Direct Glucose Uptake Measurement

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