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2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
| Molecular Weight | 358.17 |
| CAS Number | 93515-00-5 |
| Solubility (25°C) | DMF 30 mg/mL DMSO 30 mg/mL Ethanol 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] G M Brown, et al. Binding sites for 2-[125I]iodomelatonin in the adrenal gland
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