Thyroid Hormone Receptor Thyroid Hormone Receptor (THR)

Inhibitor/Activator

Cat.No.	Name	Information
M29567	DS08210767	DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
M28509	KB130015	KB130015 (KB015) is an orally active and potent ThRα and ThRβ (Thyroid Hormone Receptor) inhibitor, with IC50 values of 4.5 and 5.1 μM, respectively. KB130015 has antiarrhythmic properties. KB130015 markedly slows the kinetics of inactivation of Na+ channels. KB130015 opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle.
M27948	Protirelin acetate	Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
M27675	Taltirelin	Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release).