Inhibitor/Activator
| Cat.No. | Name | Information |
|---|---|---|
| M13964 | AZP-531 | AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. |
| M13963 | Anamorelin hydrochloride | Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay. |
| M11344 | JMV 2959 | JMV 2959 is a growth hormone secretin receptor type 1A (GHS-R1A) antagonist that acts on LC-PK1 cells and inhibits GHS-R1A with an IC50 value of 32±3 nM. |
| M8093 | Capromorelin tartrate | Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). |
| M6962 | Ibutamoren mesylate | Ibutamoren (MK 0677) mesylate is a high affinity ghrelin receptor agonist. |
| M3739 | Anamorelin | Anamorelin aims to address the symptoms by mimicking the effects of the so-called “hunger hormone” ghrelin, which is secreted by the stomach. |
| M56195 | L-692585 | L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a Ki of 0.8 nM. |
| M56194 | PF-6870961 | PF-6870961 is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. |
| M56193 | PF-6870961 hydrochloride | PF-6870961 hydrochloride is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. |
| M54369 | des-Gln14-Ghrelin | des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. |
| M54349 | Obestatin(rat) | Obestatin(rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. |
| M53166 | Human growth hormone-releasing factor | Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. |
| M53165 | [His1, Nle27] GHRF (1-32), amide, human | [His1,Nle27] GHRF (1-32), amide, human is a Growth hormone releasing hormone (GHRH) analog. |
| M53164 | Obestatin(rat) TFA | Obestatin(rat) TFA, encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. |
| M53163 | GHRF, porcine | GHRF, porcine is a growth hormone releasing factor (GHRF) peptide (porcine). |
| M53162 | GHRF, bovine | GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). |
| M41830 | PF-04628935 | PF-04628935 is a potent ghrelin receptor inverse agonist, with an IC50 of 4.6 nM. |
| M31029 | K-(D-1-Nal)-FwLL-NH2 TFA | K-(D-1-Nal)-FwLL-NH2 TFA is a high affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). K-(D-1-Nal)-FwLL-NH2 blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways. |
| M30953 | Macimorelin acetate | Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS). |
| M30783 | YIL781 | YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL-781 hydrochloride inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively. |
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