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E3 Ligase Ligand-Linker Conjugates E3 Ligase Ligand-Linker Conjugates

Inhibitor

Cat.No.  Name Information
M57091 (S,R,S)-AHPC-C3-NH2 dihydrochloride (S,R,S)-AHPC-C3-NH2 (dihydrochloride) is the dihydrochloride form of (S,R,S)-AHPC-C3-NH2.
M57090 (S,R,S)-AHPC-C7-amine hydrochloride (S,R,S)-AHPC-C7-amine (VH032-C7-amine) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader.
M57089 (S,R,S)-AHPC-C8-NH2 dihydrochloride (S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader.
M57088 Boc-A 410099.1 amide-alkylC4-amine  Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-alkylC4 linker with terminal amine.
M57087 (S,R,S)-AHPC-C7-amine dihydrochloride (S,R,S)-AHPC-C7-amine dihydrochloride is the dihydrochloride form of (S,R,S)-AHPC-C7-amine.
M57086 Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride  Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
M57085 (S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride (S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and an alkyl linker used for PROTAC degrader.
M43410 Cereblon inhibitor 2 Cereblon inhibitor 2 is a Cereblon inhibitor useful in solid tumor research, especially breast cancer.
M43409 Pomalidomide-C7-NH2 hydrochloride Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate.
M31273 Thalidomide-NH-PEG2-C2-NH-Boc  Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology.
M31272 Thalidomide-C2-amido-C2-COOH  Thalidomide-C2-amido-C2-COOH incorporates a CRBN ligand for the E3 ubiquitin ligase, and a linker. Thalidomide-C2-amido-C2-COOH can be used to design PROTAC CDK2/9 Degrader-1.




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