| Cat.No. | Name | Information |
|---|---|---|
| M2412 | AZ20 | AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR. |
| M1998 | KU-60019 | KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM. |
| M5138 | Mirin | Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity. |
| M1801 | KU-55933 | KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR). |
| M55924 | KU 59403 | KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively. |
| M55923 | SKLB-197 | SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. |
| M55921 | ATR-IN-4 | ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. |
| M55920 | M3541 | M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. |
| M55919 | (Rac)-Lartesertib | (Rac)-Lartesertib ((Rac)-M4076; (Rac)-ATM Inhibitor-5) is an isoform of Lartesertib, which is a potent inhibitor of serine/threonine protein kinase ATM. |
| M55918 | ATM Inhibitor-10 | ATM Inhibitor-10, a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). |
| M55625 | XRD-0394 | XRD-0394 is a potent and specific, orally bioavailable dual inhibitor of ATM and DNA-PKcs. XRD-0394 significantly enhanced tumor cell kill in the setting of therapeutic ionizing irradiation in vitro and in vivo. XRD-0394 also potentiates the effectiveness of topoisomerase I inhibitors in vitro. |
| M41411 | ATR-IN-24 | ATR-IN-24 is a ATR inhibitor. |
| M41410 | ATM Inhibitor-6 | ATM inhibitor-6 (A-193) is a selective ATM kinase inhibitor. |
| M41409 | ATR-IN-21 | ATR-IN-21 is a potent ATR inhibitor with an IC50 value of <1000 nM. |
| M41408 | ATR-IN-23 | ATR-IN-23 is a potent and selective ATR inhibitor with an IC50 of 1.5 nM. |
| M41407 | ATR-IN-29 | ATR-IN-29 is a potent and orally active ATR kinase inhibitor with an IC50 value of 1 nM. |
| M41406 | ATM Inhibitor-8 | ATM Inhibitor-8 is a highly potent, selective and orally active ATM inhibitor,with an IC50 of 1.15 nM. |
| M41405 | A011 | A011 is a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor with an IC50 value of 1.0 nM. |
| M41404 | ATM Inhibitor-9 | ATM Inhibitor-9 is a potent ATM inhibitor with IC505 nM for ATM kinase, useful in cancer research. |
| M29678 | Lartesertib | Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM. |
| M13589 | Elimusertib hydrochloride | Elimusertib (BAY 1895344) hydrochloride is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
