| Cat.No. | Name | Information |
|---|---|---|
| M38958 | (±)-Pinocembrin | (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line. |
| M38953 | Hydrocortisone 17-butyrate | Hydrocortisone 17-butyrate is an adrenocortico hormone. It can be used to construct animal models of atopic dermatitis. |
| M38946 | Cannabisin F | Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2. |
| M38937 | N6-(2-Hydroxyethyl)adenosine | N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| M38921 | Riddelline | Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver. |
| M38915 | Vanicoside B | Vanicoside B targets cyclin-dependent kinase 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis. |
| M38913 | Ethephon | Ethephon is a plant growth regulator. |
| M38888 | 4-Dimethylaminopyridine | 4-Dimethylaminopyridine (DMAP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M38859 | 4,4'-Dimethoxychalcone | 4,4'-Dimethoxychalcone acts as a natural autophagy inducer with anti-ageing properties. |
| M38846 | Physalin A | Physalin A induces apoptosis associated with up-regulation of caspase-3 and caspase-8 expression. Physalin A induces autophagy, found to antagonize apoptosis in HT1080 cells. Physalin A has the potential for the research of cancer disease. |
| M38828 | Alphitolic acid | Alphitolic acid (Aophitolic acid) blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research. |
| M38826 | Cardanol monoene | Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells. |
| M38824 | Kuguaglycoside C | Kuguaglycoside C is a triterpene glycoside that induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF). |
| M38823 | Phytosphingosine | Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells. |
| M38807 | Umifenovir | Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. |
| M38767 | Abyssinone V | Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity. |
| M38764 | Indinavir | Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor. |
| M38760 | Glycoborinine | Glycoborinine, a natural carbazole alkaloid, can be isolated from Glycosmis pentaphylla. Glycoborinine induces HepG2 cell apoptosis through mitochondrial pathway. Glycoborinine also inhibits HIV replication in cells. |
| M38728 | (±)-Pinoresinol | (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity. |
| M38723 | Demethoxyencecalin | Demethoxyencecalin is a chromene isolated from Helianthus annuus, has antifungal activities. |
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