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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M40870 RVT-3101 RVT-3101 is a potential first-in-class anti-tumor necrosis factor (TNF)-like ligand 1A (TL1A) monoclonal antibody for use in studies related to inflammatory bowel disease (IBD).
M40854 Elranatamab Elranatamab is a humanized IgG2ҡ bispecific T-cell inducing antibody that targets CD3 and B-cell maturation antigen (BCMA) on the surface of T-cells, resulting in activation of T-cells and the release of a variety of pro-inflammatory cytokines that lead to multiple myeloma cell lysis. It can be used in studies related to relapsed or refractory multiple myeloma (RRMM).
M40646 CDX-1140 CDX-1140 is an anti-CD40 human IgG2 monoclonal antibody that activates dendritic cells and B cells and drives NF-kB stimulation in CD40-expressing reporter cell lines.
M40611 PF-04236921 PF-04236921 is a fully human IgG2 monoclonal antibody targeting the interleukin IL-6 for studies related to Crohn's disease and rheumatoid arthritis.
M40609 Eblasakimab Eblasakimab is a potential first-in-class, novel monoclonal antibody that targets the IL-13 receptor alpha 1 subunit (IL-13Rα1) and inhibits signaling of the pro-inflammatory cytokines IL-4 and IL-13. It can be used in studies related to atopic dermatitis (AD).
M40602 Alacizumab Alacizumab is a monoclonal antibody against VEGFR2 that can be used in cancer-related studies.
M40600 Ebronucimab Ebronucimab is a monoclonal antibody to PCSK9 that can be used in studies related to hypercholesterolemia.
M40598 Serclutamab Serclutamab is a monoclonal antibody to EGFR that can be used in studies related to solid tumors.
M40597 Ametumumab Ametumumab is a recombinant fully human anti-EGFR monoclonal antibody that can be used in studies related to colorectal cancer.
M40596 Pimurutamab Pimurutamab is a monoclonal antibody to EGFR that can be used in tumor-related studies.
M40595 Pidilizumab Pidilizumab is a monoclonal antibody to PD-1 that can be used in studies related to diffuse large B-cell lymphoma (DLBCL).
M40594 Genolimzumab Genolimzumab is a PD-1 monoclonal antibody that can be used in studies related to peripheral T-cell lymphoma (PTCL).
M40593 Brolucizumab Brolucizumab is a humanized single-chain anti-VEGF-A variable antibody fragment (scFv) that can be used in studies related to macular degeneration.
M40592 Certolizumab Certolizumab is a recombinant, polyethylene glycolated, antigen-binding fragment of a humanized monoclonal antibody that selectively targets and neutralizes tumor necrosis factor (TNF)-alpha, and may be used in psoriasis-related studies.
M40552 Osemitamab Osemitamab (TST001) is a recombinant humanized, IgG1 antibody targeting CLDN18.2, consisting of the human mouse monoclonal TST001 γ-1 chain polymerized via disulfide bonding with the human mouse monoclonal TST001 κ-chain dimer (ACI). It can be used in studies related to bile duct tumors.
M31300 Faricimab Faricimab is a bispecific antibody targeting Ang II and VEGF-A for studies related to eye disease and cardiovascular disease.
M31299 Zebituzumab Zebituzumab (zebituzumab) is a recombinant human-mouse chimeric anti-CD20 monoclonal antibody that can be used in studies related to CD20-positive diffuse large B-cell lymphoma.
M31121 Dinutuximab Dinutuximab is an anti-disialytic ganglioside antigen (GD2) antibody with anticancer activity for studies related to pediatric neuroblastoma.
M25443 Necitumumab Necitumumab is a second-generation fully humanized immunoglobulin G1 (IgG1), epidermal growth factor (EGFR) receptor monoclonal antibody that specifically blocks the ligand binding site of EGFR.
M25387 Daclizumab Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA.

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