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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M54550 Stapokibart Stapokibart is a humanized monoclonal antibody targeting IL-4Rα that blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit, IL-4Rα. Stapokibart is able to interact with IL-4Rα in humans, cynomolgus monkeys, and rats, and can be used in atopic dermatitis research.
M54549 AZD3152 AZD3152 is a monoclonal antibody targeting SARS-CoV-2.
M54548 Benmelstobart Benmelstobart is an anti-PD-L1 humanized IgG1ҡ monoclonal antibody that can be used for tumor-related studies.
M54528 Dargistotug Dargistotug is a fully human IgG1 monoclonal antibody targeting T-cell immunoglobulin and the ITIM structural domain (TIGIT) that induces an immune response targeting cancer cells by blocking the TIGIT pathway.
M54521 Narlumosbart Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB).
M50212 PRX012 PRX012 is a potential best-in-class (BIC) anti-amyloid β (Aβ) monoclonal antibody that stimulates microglia-mediated clearance of amyloid deposits in brain tissues, and can be used in studies related to Alzheimer's disease (AD).
M50211 AL-002 AL-002 is a humanized monoclonal antibody targeting myeloid triggered receptor 2 (TREM2) that improves cell survival and proliferation and increases microglia activity by activating TREM2 signaling, and can be used in studies related to Alzheimer's disease (AD).
M50201 BAY-3401016 BAY-3401016 is a monoclonal antibody targeting SEMA3A for studies related to Alport syndrome.
M50200 BAY-3018250 BAY-3018250 is a monoclonal antibody targeting α2-antifibrinolytic enzyme (A2AP) for use in studies related to cardiovascular disease.
M50169 IPG0521 IPG0521 is a bifunctional antibody targeting CCR8, which can block CCR8 signaling with high intensity and weak ADCC function, and can effectively inhibit the growth of multiple tumor types in homologous and immunohumanized mouse models.
M50168 IPGA05 IPGA05 is a monoclonal antibody targeting CCR8 for tumor-related studies.
M50167 PSB-114 PSB-114 is an ADCC-enhanced targeted CCR8 humanized monoclonal antibody that removes tumor-associated CCR8-expressing Tregs and can be used in tumor-related studies.
M50166 ZL-1218 ZL-1218 is a novel anti-CCR8 antibody that can be used in studies related to solid tumors.
M50165 HBM1022 HBM1022 is an anti-CCR8 fully human monoclonal antibody for use in studies related to solid tumors.
M50164 CM369 CM369 is a potential first-of-its-kind (first-in-class) anti-chemokine receptor 8 (CCR8) monoclonal antibody that binds specifically to CCR8 on Treg and removes immunosuppressive Treg through ADCC action to relieve tumor suppression in the TME.CM369 can be used in studies related to advanced solid tumors.
M50163 BGB-A3055 BGB-A3055 is a monoclonal antibody targeting CCR8 for studies related to solid tumors.
M50162 AMG-355 AMG-355 is a monoclonal antibody targeting CCR8 for studies related to solid tumors.
M50160 SRF-114 SRF-114 is a human IgG1 anti-CCR8 monoclonal antibody that targets tumor Treg cells and induces antibody-dependent cell-mediated cytotoxicity (ADCC) through activation of NK cells, resulting in selective depletion of immunosuppressive tumor T regulatory cells (Tregs) while preserving peripheral Tregs. It can be used for tumor-related studies.
M50159 S-531011 S-531011 is a novel anti-human IgG1 antibody that exhibits in vitro antibody-dependent cytotoxicity against CCR8-expressing cells and neutralizing activity against the CCL1-CCR8 signaling pathway. It can be used in studies related to solid tumors.
M50158 LM-108 LM-108 is a novel anti-CCR8 monoclonal antibody that efficiently eliminates tumor-associated Tregs in a mouse model through antibody-dependent cell-mediated cytotoxicity (ADCC) without affecting peripheral Tregs, showing potent anti-tumor activity, and can be used for tumor-related studies.

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