| Cat.No. | Name | Information |
|---|---|---|
| M3648 | HO-3867 | HO-3867, an analog of curcumin, is a selective STAT3 inhibitor. |
| M3982 | Cryptotanshinone | Cryptotanshinone is a potent anticancer agent targeting the activation STAT3 protein with antitumor activity. |
| M3970 | Scutellarin | Scutellarin, an active flavone isolated from Scutellaria baicalensis, is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively. Scutellarin inhibited caspase-11 activation and pyroptosis in macrophages at least partly via regulating the PKA signaling pathway. |
| M2883 | Nifuroxazide | Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. |
| M2028 | Fludarabine (NSC 118218) | Fludarabine is a STAT1 activation inhibitor and a DNA synthesis inhibitor. |
| M3032 | Stattic | Stattic is the first nonpeptidic STAT3 inhibitor, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM, highly selectivity over STAT1. Stattic inhibits STAT3 phosphorylation (at Y705 and S727). |
| M7747 | Diosgenin | Diosgenin is a plant steroid which induces apoptosis in colon cancer cell lines and induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. |
| M4433 | Alantolactone | Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone (helenin, helenine, Eupatal) could induce activin/SMAD3 signaling and disrupt Cripto-1/activin receptor type II A interaction. |
| M9706 | Colivelin TFA | Colivelin TFA is a brain penetrant neuroprotective peptide and a potent activator of STAT3. |
| M10077 | Colivelin | Colivelin is a brain penetrant neuroprotective peptide and a potent activator of STAT3. |
| M49674 | PM-81I | PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. |
| M49673 | OSM-SMI-10B | OSM-SMI-10B a derivative of OSM-SMI-10. |
| M49672 | Neocucurbitacin A | Neocucurbitacin A is STAT3 inhibitor a compound extracted from Aquilaria crassna pericarp. |
| M49671 | MMPP | MMPP is an anti-inflammatory agent. |
| M49670 | MC0704 | MC0704 is a STAT3 inhibitor with an IC50 value of 2.13 μM. |
| M49669 | HODHBt | HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. |
| M49668 | HJC0416 hydrochloride | HJC0416 hydrochloride is a potent and orally active STAT3 inhibitor with an enhanced anticancer profile than Stattic. |
| M49667 | HJC0149 | HJC0149 is a potent and orally active inhibitor of signal transducer and activator of transcription 3 (STAT3). |
| M49666 | Eucannabinolide | Eucannabinolide is a STAT3 inhibitor. |
| M49665 | CMD178 | CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development. |
| M49664 | APT STAT3 | APT STAT3 is a specific STAT3-binding peptide. |
| M49663 | Antitumor agent-73 | Antitumor agent-73 is a Diosgenin derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. |
| M49662 | Angoline hydrochloride | Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. |
| M49661 | Salviolone | Salviolone is a natural diterpenoid derivative that can against melanoma cells. |
| M49660 | STX-0119 | STX-0119 is a selective, orally active STAT3 dimerization inhibitor. |
| M49659 | MNK8 | MNK8 is a potent STAT3 (signal transducer and activator of transcription 3) inhibitor. |
| M49658 | ML115 | ML115 is a molecular probe of the signal transducer and activator of transcription (STAT3). |
| M49657 | LLL12 | LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. |
| M49655 | HP590 | HP590 is an orally active, novel and potent STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM; ATP inhibition: IC50=24.7 nM). |
| M49654 | APTSTAT3-9R | APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
