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Abmole Inhibitor Catalog 2017

PPAR Peroxisome Proliferator Activated Receptor

Inhibitors

Cat.No.  Name Information
M5940 Rosiglitazone HCl Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
M5927 Retinoic acid All-trans retinoic acid (ATRA; Vitamin A acid) has been widely investigated for treatments of many cancers including prostate cancer.
M5878 Pioglitazone HCl Pioglitazone HCl is a selective peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist, used to treat diabetes.
M5641 Fenofibric acid Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.
M5530 Clofibrate Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.
M5171 Troglitazone (CS-045) Troglitazone is a potent agonist for the peroxisome proliferator-activated receptor-(PPAR) that is a ligand activated transcription factor regulating cell differentiation and growth.
M3658 GW501516 GW501516 is a potent and highly selective PPARβ/δ agonist, with EC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.
M3635 FH535 FH535 is a compound that suppresses both Wnt/beta-catenin and peroxisome proliferator-activated receptor (PPAR) signaling.
M3044 T0070907 T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity over PPARα and PPARδ.
M2748 GW9662 GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ.
M2747 GW7647 GW7647 is a potent and highly selective PPARα agonist with EC50 of 6 nM.
M2742 GW0742 GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.
M2732 GSK0660 GSK0660 is a selective PPARδ antagonist with IC50 of 155 nM.
M2335 ZLN005 ZLN005 is a novel and potent small molecule PGC-1α transcriptional activator.
M2200 Ciprofibrate Ciprofibrate is a peroxisome proliferator-activated receptor α (PPARα) agonist.
M2038 Rosiglitazone maleate Rosiglitazone maleate (Avandia) is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM.
M2033 GSK 3787 GSK3787 is an orally available selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6).
M1894 Rosiglitazone Rosiglitazone is a selective ligand of peroxisome proliferator-activated receptor gamma (PPARgamma).
M1880 WY 14643 WY 14643 (Pirinixic Acid) is a potent and selective, peroxisome proliferator-activated receptor-α (PPARα) agonist.


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