About 4 results found for searched term "pan-KRAS-IN-2" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41919 | pan-KRAS-IN-2 | Ras |
| pan-KRAS-IN-2 is a pan inhibitor of with IC50s ≤10 nM for KRAS WT and mutants (G12D, G12C, G12V, G12S, G12A, Q61H), and ＞10 μM for KRAS G13D, respectively. | ||
| M21518 | MRTX849 ethoxypropanoic acid | PROTAC Linker |
| MRTX849 ethoxypropanoic acid incorporates a ligand for KRAS G12C, and a PROTAC linker. MRTX849 ethoxypropanoic acid can be used in the synthesis of PROTAC LC-2. | ||
| M40499 | BI-2865 | Ras |
| BI-2865 is a non-covalent pan-KRAS inhibitor that binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with Kd values of 6.9 nM, 4.5 nM, 32 nM, 26 nM, and 4.3 nM, respectively.It can be used in studies related to KRAS mutant tumors. | ||
| M41924 | pan-KRAS-IN-4 | Ras |
| pan-KRAS-IN-4 is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively. | ||
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