About 1 result found for searched term "ZAK-IN-1" (0.107 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M66381 | ZAK-IN-1 | MAPKAPK2/MAP3K/MAP4K |
| ZAK-IN-1 is an orally active and selective selective leucine-zipper and sterile‑α motif kinase (ZAK) inhibitor with IC50 of 4 nM and KD of 8 nM. ZAK-IN-1 exhibits excellent selectivity against a panel of 403 wild-type kinases. ZAK-IN-1 blocks p38/GATA-4 and JNK/c-Jun signaling and shows promising anti antihypertrophic cardiomyopathy (HCM) efficacy. | ||
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