About 1 result found for searched term "YZ129 " (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28763 | YZ129 | HSP |
| YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration. | ||
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