About 20 results found for searched term "Xanthine Oxidase" (0.257 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11362 | Xanthine Oxidase | Metabolite/Endogenous Metabolite |
| EC 1.1.3.22 | ||
| Xanthine oxidase (XOD) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid. | ||
| M42623 | Xanthine oxidase-IN-10 | Xanthine Oxidase |
| Xanthine oxidase-IN-10 (XO8 analog) is an xanthine oxidase (XO) inhibitor. | ||
| M42624 | Xanthine oxidase-IN-11 | Xanthine Oxidase |
| Xanthine oxidase-IN-11 (XO8 analog) is an xanthine oxidase (XO) inhibitor. | ||
| M1711 | Febuxostat (TEI-6720) | Xanthine Oxidase |
| TEI-6720; Uloric; TMX-67 | ||
| Febuxostat (TEI-6720) is a non-purine selective xanthine oxidase inhibitor with IC50 of 114 -210 nM. | ||
| M3302 | Allopurinol | Xanthine Oxidase |
| Allopurinol is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. | ||
| M3322 | Allopurinol Sodium | Xanthine Oxidase |
| Allopurinol Sodium is a xanthine oxidase inhibitor and a structural isomer of hypoxanthine with an IC50 of 7.82 ± 0.12 μM, which inhibits the conversion of xanthine to uric acid and increases the reuse of hypoxanthine and xanthine in nucleic acid synthesis, thereby reducing serum and urinary uric acid levels, and can be used in gout-related studies. | ||
| M45272 | RLBN-1127 | URAT1 |
| RLBN-1127 is an inhibitor of URAT1 and xanthine oxidase (XO) and can be used in studies related to non-alcoholic fatty liver disease (NAFLD) and gout. | ||
| M4564 | Lobetyolin | Apoptosis |
| Lobetyolin is a bioactive compound isolated from Codonopsis Pilosula. Lobetyolin has anti-inflammatory, antioxidant and xanthine oxidase inhibitory activities. Lobetyolin also induces apoptosis by inhibiting ASCT2-mediated glutamine metabolism. | ||
| M6970 | ML171 | NADPH Oxidase |
| 2-Acetylphenothiazine; 2-APT | ||
| ML171 is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively. ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay. | ||
| M11115 | Broussoflavonol F | Xanthine Oxidase |
| Broussoflavonol F has xanthine oxidase inhibitory activity. | ||
| M19179 | Prudomestin | Xanthine Oxidase |
| Prudomestin, isolated from the heartwood of Prunus domestica, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6 µM). | ||
| M39183 | 7,8,3′,4′-Tetrahydroxyflavone | Xanthine Oxidase |
| 7,8,3′,4′-Tetrahydroxyflavone (compound 2) is a potent xanthine oxidase (XOD) inhibitor with an IC50 value of 10.488 µM. | ||
| M39184 | Forsythoside F | Xanthine Oxidase |
| Forsythoside F (Arenarioside) is a xanthine oxidase inhibitor and possesses antihyperuricemic effects in vivo. | ||
| M39185 | Fraxamoside | Xanthine Oxidase |
| Fraxamoside is a competitive xanthine oxidase inhibitor with an IC50 of 16.1 μM and a Ki of 0.9 μM. | ||
| M42272 | URAT1&XO inhibitor 2 | Xanthine Oxidase |
| URAT1&XO inhibitor 2 is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. | ||
| M42622 | URAT1&XO inhibitor 1 | Xanthine Oxidase |
| URAT1&XO inhibitor 1 is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). | ||
| M44848 | Ellagic acid-4-O-beta-D-xylopyranoside | Xanthine Oxidase |
| Ellagic acid 4-O-β-D-xylopyranoside is a natural ellagitannin with antimicrobial activity. Ellagic acid 4-O-β-D-xylopyranoside is an xanthine oxidase inhibitor with an 50 of 2.1 μg/mL. | ||
| M45273 | TEI-6469 | Xanthine Oxidase |
| TEI-6469 is a xanthine oxidase (XO) inhibitor that may be used in studies related to gout. | ||
| M49844 | 6-Formylpterin | Apoptosis |
| 6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells. | ||
| M58176 | Purpurogallin | Xanthine Oxidase |
| Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 µM. Purpurogallin has antioxidant and anti-inflammatory effects. | ||
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