About 4 results found for searched term "X-α-Gal" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9448 | X-α-Gal | Others |
| X-alpha-Gal | ||
| X-α-Gal is suitable as a substrate for α-galactosidase. | ||
| M4539 | Polygalasaponin-F | TLR |
| Polygalasaponin F is an oleanane type triterpenoid saponin extracted from Polygala Japonica, which can reduce the release of inflammatory cytokine tumor necrosis factor α (TNFa). Polygalasaponin F reduces the secretion of neuroinflammatory cytokines by regulating the TLR4-PI3K/ Akt-NF-KB signaling pathway. | ||
| M30181 | D77 | HIV Protease |
| D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells). IC50 value: 23.8 μg/ml (EC50, in MT-4 cell ), 5.03 μg/ml (EC50, in C8166 cell) Target: HIV-1 in vitro: D77 exhibits a highly specific binding affinity to HIV-1 integrase catalytic core domain.D77 induces a dramatic concentration-dependent decrease of α-galactosidase activity compared to the D77-untreated cells. D77 reveals a significant inhibition activity against the interaction of IN with IBD. | ||
| M30575 | Migalastat hydrochloride | Others |
| DGJ; 1-Deoxygalactonojirimycin; GR181413A | ||
| Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. | ||
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