About 1 result found for searched term "VU10010 " (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30397 | VU10010 | AChR/AChE |
| VU10010 is a potent, highly selective and allosteric M4 mAChR potentiator with an EC50 of 400 nM. VU10010 binds to an allosteric site on M4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus. | ||
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