About 5 results found for searched term "Urolithin D" (0.175 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43493 | Urolithin D | Ephrin Receptor |
| Urolithin D is competitive and reversible antagonist of EphA receptors. | ||
| M8600 | Urolithin B | NF-κB |
| Urolithin B is a natural product with antiproliferative and antioxidant activity. | ||
| M8666 | Urolithin A | ERK |
| Urolithin A is a naturally occurring compound produced by the metabolism in the body of vegetable tannins (ellagic acid and ellagitannins) found in food. It is also a mitochondrial modulator, regulating mitochondrial function in hematopoietic stem cells, as well as restoring blood regeneration in aging hematopoietic stem cells. In addition, Urolithin A is a ligand for the Aromatic Hydrocarbon Receptor (AhR), which promotes the anti-tumor function of CD8+ cytotoxic T-lymphocytes (CTLs) in an AhR-independent manner. Moreover, Urolithin A directly binds to ERK1/2 kinase, enhances its activation, and subsequently phosphorylates and activates the autophagy initiation factor ULK1, thereby promoting autophagy. | ||
| M11316 | Urolithin C | Calcium Channel |
| Urolithin C, a polyphenol intestinal microbial metabolite of ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is an L-type Ca2+ channel opening agent that enhances Ca2+ influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondria mediated pathway. | ||
| M58952 | Urolithin M7 | Metabolite/Endogenous Metabolite |
| 3,8,10-trihydroxy urolithin | ||
| Urolithin M7 is a metabolite, which is derived from the transformation of ellagitannins, compounds found predominantly in pomegranates, berries, and nuts. This transformation occurs via intestinal microbiota, which convert ellagitannins into various urolithins, including Urolithin M7. Its mode of action involves influencing cellular processes, potentially modulating mitochondrial function and autophagy pathways. | ||
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