About 2 results found for searched term "Tenapanor" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7572 | Tenapanor | Na+/H+ Exchanger (NHE) |
| AZD1722; RDX5791 | ||
| Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively. | ||
| M28002 | Tenapanor hydrochloride | Na+/H+ Exchanger (NHE) |
| AZD1722 hydrochloride; RDX5791 hydrochloride | ||
| Tenapanor (AZD1722) hydrochloride is a first-in-class, potent, orally active sodium/hydrogen exchange isomer 3 (NHE3) inhibitor that reduces intestinal phosphate absorption primarily by decreasing passive paracellular phosphate flux. Tenapanor hydrochloride reduces intestinal absorption of phosphate by reducing passive paracellular phosphate flux. Tenapanor hydrochloride is used in studies related to chronic renal insufficiency, hyperphosphatemia, constipation, and irritable bowel syndrome. | ||
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