About 27 results found for searched term "Taxin B" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M16542 | Taxin B | Diterpenoids |
| Taxin B | ||
| M38933 | Taxinine B | Microtubule |
| Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells. | ||
| M3700 | PF8380 | PDE |
| Pf-8380 is a potent autotaxin inhibitor with IC50 of 2.8 nM and 101 nM in in vitro enzyme assay and human whole blood cell assay, respectively. | ||
| M3942 | Cephalotaxine | Anti-infection |
| (-)-Cephalotaxine; ZINC19795976 | ||
| Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia. | ||
| M3965 | Homoharringtonine | Alkaloids |
| Omacetaxine mepesuccinate,HHT | ||
| Homoharringtonine is a cephalotaxine alkaloid which inhibits the formation of diphenylalanine and acetylphenylalanyl-puromycin in liver ribosomes. | ||
| M4964 | HA130 | PDE |
| HA-130 | ||
| HA130 is a selective ATX (autotaxin) inhibitor with IC50 of 28 nM. | ||
| M6287 | GLPG1690 | PDE |
| Ziritaxestat | ||
| Ziritaxestat (GLPG1690) is a first-in-class autotaxin (ATX) inhibitor, with IC50 of 131 nM and Ki of 15 nM. | ||
| M7238 | S 32826 | Others |
| S 32826 is a potent autotaxin inhibitor. | ||
| M9944 | 7,4'-Dihydroxyflavone | CCR |
| 7,4'-Dihydroxyflavone, a flavonoid isolated from Glycyrrhiza uralensis, is an eotaxin/CCL11 inhibitor. | ||
| M10005 | Recombinant Human CXCL1 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Chemokine (C-X-C motif) Ligand 1 | ||
| Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family. | ||
| M10809 | CRT0273750 | PDE |
| CRT0273750 is a lead compound of autotaxin (ATX) inhibitors and regulates plasma LPA levels. CRT0273750 can be used in ATX/LPA dependent cancer models. | ||
| M11451 | Autotaxin modulator 1 | PDE |
| Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors. | ||
| M11452 | PAT-505 | PDE |
| PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma, respectively. | ||
| M15016 | Recombinant Human Eotaxin-2/CCL24 (E. coli) | Cytokines and Growth Factors |
| C-C motif chemokine 24; CK-beta-6 | ||
| Recombinant human Eotaxin-2/CCL24 protein (E. coli) is a new CC chemokine recently discovered. It is produced by activated monocytes and T lymphocytes. Protein structure: CCL24 (VAL27-ALA104), Accession # : O00175. | ||
| M16526 | Taxinine M | Diterpenoids |
| Taxinine M is a tetracyclic taxane, which can be isolated from Taxus brevifolia. | ||
| M21275 | ONO-8430506 | PDE |
| ONO-8430506 is a potent autotaxin phosphodiesterase inhibitor with significant oral exposure and low clearance in higher species. | ||
| M25221 | Bertilimumab | CCR |
| CAT 213; iCo-008 | ||
| Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research. | ||
| M25411 | Recombinant Human CXCL1 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 1 | ||
| Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. | ||
| M28698 | Autotaxin-IN-1 | PDE |
| Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship. Autotaxin-IN-1 is used in treatment of osteoarthritis pain. | ||
| M28851 | Cudetaxestat | PDE |
| BLD-0409 | ||
| Cudetaxestat (BLD-0409) is a potent and orally active autotaxin (ATX) inhibitor. | ||
| M29313 | BI-2545 | PDE |
| BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively. | ||
| M31401 | PAT-347 | PDE |
| PAT-347 is an Autotaxin (ATX) inhibitor. | ||
| M40217 | Demethylcephalotaxinone | Others |
| Demethylcephalotaxinone is an alkaloid. Demethylcephalotaxinone can be isolated from Hainan cycad (C. hainanensis). | ||
| M49394 | BBT-877 | PDE |
| BBT-877 is an oral small molecule autotaxin (ATX) inhibitor for use in studies related to non-alcoholic steatohepatitis (NASH) and idiopathic pulmonary fibrosis (IPF). | ||
| M49398 | ATX inhibitor 5 | PDE |
| ATX inhibitor 5 is a potent, orally active inhibitor of Autotaxin (ATX) with an IC50 of 15.3 nM.Additionally, AATX inhibitor 5 exhibits anti-hepatic fibrosis activity and significantly reduces CCl4-induced hepatic fibrosis. | ||
| M49401 | Autotaxin-IN-3 | PDE |
| Autotaxin-IN-3 is an Autotaxin(ATX) inhibitor with an IC50 value of 2.4 nM. | ||
| M49402 | (E/Z)-HA155 | PDE |
| (E/Z)-HA155 is a potent Autotaxin (ATX) type I inhibitor for studies related to cancer, fibrous disorders, inflammation, pain and angiogenesis. | ||
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