About 15 results found for searched term "Tau Protein" (0.251 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42712 | Tau protein aggregation-IN-1 | Tau Protein |
| Tau protein aggregation-IN-1 is a Tau protein aggregation inhibitor. | ||
| M52406 | Tau protein (592-597), human TFA | Tau Protein |
| Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. | ||
| M54752 | Recombinant Human Tau Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| MAPT; microtubule-associated protein tau | ||
| Tau proteins are proteins that stabilize microtubules. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. | ||
| M54754 | Recombinant Human Tau-F Protein (E.coli) | Cytokines and Growth Factors |
| Microtubule-associated protein tau; MAPTL | ||
| Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. | ||
| M2066 | Staurosporine | PKC |
| AM-2282; STS; CGP 41251 | ||
| Staurosporine (AM-2282) is a potent ATP-competitive kinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively. | ||
| M4096 | Saikosaponin-C | Amyloid |
| Saikosaponin C, the active ingredient in Bupleurum, mainly targets amyloid beta and tau proteins in ALZHEIMER's disease. Saikosaponin C inhibited the release of Aβ1-40 and Aβ1-42, and inhibited abnormal tau phosphorylation, but had no effect on BACE1 activity and expression. | ||
| M5375 | 6-Mercaptopurine (6-MP) Monohydrate | DNA/RNA Synthesis |
| 6-MP | ||
| Mercaptopurine inhibits purine nucleotide synthesis and metabolism by inhibiting phosphoribose pyrophosphate amide transferase (PRPP amide transferase). PRPP amide transferase is a rate-limiting enzyme formed by purine. It alters the synthesis and function of RNA and DNA. Mercaptopurine also interferes with nucleoside tautomies and glycoprotein synthesis. | ||
| M14554 | Leucomethylene blue mesylate | Amyloid |
| TRx0237 mesylate; Methylene blue leuco base mesylate | ||
| Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. | ||
| M24912 | Tilavonemab | Microtubule |
| ABBV-8E12; C2N-8E12 | ||
| Tilavonemab (ABBV-8E12) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates and reduces brain atrophy. Tilavonemab can be used in the study of Alzheimer's disease. | ||
| M24962 | Semorinemab | Others |
| RG 6100; RO7105705; MTAU-9937A | ||
| Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a Kd value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease. | ||
| M29108 | (-)Clausenamide | Amyloid |
| (-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD). | ||
| M29331 | Tau tracer 2 | Microtubule |
| Pl-2620 | ||
| Tau tracer 2 (Pl-2620) is a Tau tracer used for imaging Tau protein aggregates. Tau tracer 2 can be used to diagnose neurodegenerative diseases. | ||
| M29922 | PHF6 | Amyloid |
| PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein. | ||
| M42626 | Aβ/tau aggregation-IN-3 | Amyloid |
| Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. | ||
| M54691 | Leuco methylthioninium | Tau Protein |
| HMTM | ||
| Leuco methylthioninium is a tau protein aggregation inhibitor that can be used in studies related to Alzheimer's disease (AD). | ||
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