About 7 results found for searched term "TT-01" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8874 | C188-9 | STAT |
| TTI-101 | ||
| C188-9 is a small-molecule STAT3 inhibitor, can block Th2 and Th17 cell expansion and cytokine production to prevent house dust mite (HDM)-induced airway inflammation and remodeling. | ||
| M24910 | Olinvacimab | VEGFR/PDGFR |
| TTAC-0001 | ||
| Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer. | ||
| M49353 | TT-01 | HSP |
| TT-01 is a compound that targets HSP70 and can be used in studies related to vitiligo. | ||
| M14432 | FASN-IN-4 tosylate | FAS |
| FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. | ||
| M19986 | Recombinant Human CXCL6 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | ||
| Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162. | ||
| M21580 | EG-011 | Actin-Related Protein |
| EG-011 is a first-in-class, potent Wiskott-Aldrich Syndrome Protein (WASP) activator that activates the self-inhibited form of WASP via strong actin polymerization.In addition, EG-011 has selective anti-lymphoma activity. | ||
| M27803 | Leucettine L41 | CDK |
| Leucettine L41 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 µM, respectively). Leucettine L41 prevents lipid peroxidation and the accumulation of reactive oxygen species (ROS) induced by Aβ25-35 in the hippocampus in a mouse model of Alzheimer’s disease-like toxicity. Leucettine L41 also prevents memory deficits induced by Aβ25-35 in the same model. | ||
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