About 4 results found for searched term "TRAP1-IN-2" (0.142 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41509 | TRAP1-IN-2 | HSP |
| TRAP1-IN-2 is a selective TRAP1 client protein degrader, while TRAP1-IN-2 is useless for Hsp90-cytosolic clients. | ||
| M20676 | Pimitespib | HSP |
| TAS-116 | ||
| TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L). | ||
| M27954 | CBK289001 | PAR |
| CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively. | ||
| M28365 | 1-Alaninechlamydocin | HDAC |
| 1-Alaninechlamydocin, a cyclic tetrapeptide, is a potent HDAC inhibitor (IC50=6.4 nM). 1-Alaninechlamydocin induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells. | ||
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