TRAP1-IN-2 - Search Results | AbMole BioScience

About 5 results found for searched term "TRAP1-IN-2" (0.128 seconds)

Cat.No.	Name	Target
M41509	TRAP1-IN-2	HSP
	TRAP1-IN-2 is a selective TRAP1 client protein degrader, while TRAP1-IN-2 is useless for Hsp90-cytosolic clients.
M18062	3-Hydroxy-9,10-dimethoxyptercarpan	VEGFR/PDGFR
	Methylnissolin; Astrapterocarpan
	Methylnissolin (Astrapterocarpan) inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase.
M20676	Pimitespib	HSP
	TAS-116
	TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).
M27954	CBK289001	PAR
	CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively.
M28365	1-Alaninechlamydocin	HDAC
	1-Alaninechlamydocin, a cyclic tetrapeptide, is a potent HDAC inhibitor (IC50=6.4 nM). 1-Alaninechlamydocin induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells.