About 1 result found for searched term "TNO155" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M9898 | TNO155 | Phosphatase |
TNO-155;Batoprotafib | ||
TNO155 is a first-in-class, selective, orally active wild-type SHP2 metamorphosis inhibitor with an IC50 value of 0.011 µM. tNO155 has good water solubility (0.736 mM), moderate lipophilicity (LogP=1.6), high lipophilic efficiency (>6), and no hERG inhibition (IC50 >30 μM) and no phototoxicity. Does not inhibit CYP450. |
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