About 8 results found for searched term "TL13" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29383 | TL13-12 | PROTAC |
| TL13-12 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.69 nM. TL13-12 also prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 13.5 nM, 5.74 nM, 18.4 nM, and 65 nM, respectively. TL13-12 is comprised of the conjugation of TAE684 and the Cereblon ligand of Pomalidomide. | ||
| M29384 | TL13-112 | PROTAC |
| TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib and the Cereblon ligand of Pomalidomide. | ||
| M41562 | TLR7 agonist 13 | Nucleoside Antimetabolite/Analog |
| TLR7 agonist 13 is a guanosine analog. | ||
| M57185 | TL13-22 | ALK |
| TL13-22 is a negative control for TL13-12 and a potent ALK inhibitor with an IC50 of 0.54 nM. | ||
| M57184 | TL13-110 | ALK |
| TL13-110 is a negative control for TL13-112 and a potent ALK inhibitor with an IC50 of 0.34 nM. | ||
| M57864 | TL13 | Others |
| TL13 | ||
| M62441 | ABCA1 Human Pre-designed siRNA Set | siRNA |
| ATP binding cassette subfamily A member 1 | ||
| Human ABCA1 Pre-designed siRNA Set contains three designed siRNAs for ABCA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 19 | ||
| M64054 | METTL13 Human Pre-designed siRNA Set | siRNA |
| methyltransferase 13, eEF1A N-terminus and K55 | ||
| Human METTL13 Pre-designed siRNA Set contains three designed siRNAs for METTL13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 51603 | ||
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