TL13 - Search Results | AbMole BioScience

About 6 results found for searched term "TL13" (0.151 seconds)

Cat.No.	Name	Target
M29383	TL13-12	PROTAC
	TL13-12 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.69 nM. TL13-12 also prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 13.5 nM, 5.74 nM, 18.4 nM, and 65 nM, respectively. TL13-12 is comprised of the conjugation of TAE684 and the Cereblon ligand of Pomalidomide.
M29384	TL13-112	PROTAC
	TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib and the Cereblon ligand of Pomalidomide.
M41562	TLR7 agonist 13	Nucleoside Antimetabolite/Analog
	TLR7 agonist 13 is a guanosine analog.
M57185	TL13-22	ALK
	TL13-22 is a negative control for TL13-12 and a potent ALK inhibitor with an IC50 of 0.54 nM.
M57184	TL13-110	ALK
	TL13-110 is a negative control for TL13-112 and a potent ALK inhibitor with an IC50 of 0.34 nM.
M57864	TL13	Others
	TL13