About 5 results found for searched term "TIC10" (0.114 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3068 | TIC10 | Akt |
| ONC-201; Dordaviprone | ||
| TIC10 (ONC-201) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier. | ||
| M20592 | TIC10 Analogue | Akt |
| TIC10 Analogue is an analogue of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2. | ||
| M30504 | Pentachloropseudilin | Myosin |
| Antibiotic A 15104 Y; PClP | ||
| Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β. | ||
| M54224 | Adrenocorticotropic Hormone (ACTH) (4-10), human | Melanocortin Receptor |
| Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist. | ||
| M54442 | Adrenocorticotropic Hormone (ACTH) (1-10), human | Others |
| Adrenocorticotropic Hormone (ACTH) (1-10), human, an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM). | ||
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