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 About 2 results found for searched term "THZ1-R" (0.08 seconds)

Cat.No.  Name Target
M10913 THZ1-R CDK
THZ1-R is a non-cysteine-reactive analogue of THZ1 with reduced activity against CDK7 inhibition. THZ1-R in combination with CDK7 Kd 142 nM.
M13617 THZ1 Hydrochloride CDK
THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression.



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