About 1 result found for searched term "Synta66" (0.433 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8747 | Synta66 | Calcium Channel |
| Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency (IC50 = 26 nM & 43 nM based on maximum Ca2+ level & rate of increase, respectly). | ||
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