About 3 results found for searched term "Sofosbuvir (PSI-7977)" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3666 | Sofosbuvir (PSI-7977) | HCV Protease |
| Sofosbuvir, GS-7977 | ||
| Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. | ||
| M13485 | PSI-7409 | Anti-infection |
| PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV. | ||
| M55811 | PSI-7409 tetrasodium | Anti-infection |
| PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. | ||
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