Sigma-1 receptor antagonist 5 - Search Results

About 5 results found for searched term "Sigma-1 receptor antagonist 5" (0.132 seconds)

Cat.No.	Name	Target
M42704	Sigma-1 receptor antagonist 5	Sigma Receptor
	Sigma-1 receptor antagonist 5 and histamine H3 (hH3R, Ki=7.7 nM, IC50=215 nM).
M7669	BMY-14802	Sigma Receptor
	BMY-14802 is a potent and selective sigma-1 (σ1) receptor antagonist with an IC₅₀ value of approximately 100 nM.
M14060	CT1812	Sigma Receptor
	Sigma-2 receptor antagonist 1
	CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant sigma-2 (σ-2) receptor antagonist with a Ki of 8.5 nM.
M28096	S1RA hydrochloride	Sigma Receptor
	E-52862 hydrochloride
	S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization.
M28534	NE-100 hydrochloride	Sigma Receptor
	NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death.