About 1 result found for searched term "SML-8-73-1" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49367 | SML-8-73-1 | Ras |
| SML-8-73-1 is a GDP analog and also a KRAS inhibitor that irreversibly covalently binds to the GTPase active site of KRAS, and its binding rate to KRAS G12C was more than 95% in a 1 mmol/L GDP/GTP environment, and the IC 50 value for the inhibition of the proliferation of lung cancer cells H358 was 26.6 μmol/L . | ||
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