About 2 results found for searched term "SI-109" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21406 | SI-109 | STAT |
| SI-109 is a potent STAT3 SH2 domain structural domain inhibitor (Ki=9 nM) with antitumor activity. si-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). si-109 and the CRBN analogue lenalidomide ligand were used to design the PROTAC STAT3 degradation agent SD- 36. | ||
| M54645 | SION-109 | CFTR |
| SION-109 is a transmembrane conductance regulator (CFTR) modulator that targets the interface of CFTR nucleotide-binding domain 1 (NBD1) interaction with the CFTR intracellular loop 4 (ICL4) protein domain. | ||
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