About 19 results found for searched term "SAP6" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4626 | Prosapogenin-CP6 | Others |
| Prosapogenin CP6 is a natural product. | ||
| M43353 | SAP6 | Others |
| SAP6 is a biological active peptide. | ||
| M1781 | Adezmapimod (SB203580) | p38 MAPK |
| RWJ 64809; PB 203580; Adezmapimod | ||
| Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM. | ||
| M3936 | Saikosaponin D | COX |
| Ssd | ||
| Saikosaponin D is a COX-2 and iNOS inhibitor,a Saikosaponin A epimer, which Inhibits NF-κB, TNF-α, IL-1β and IL-6 and Inhibits apoptosis. | ||
| M4069 | (S)Ginsenoside-Rh1 | PPAR |
| Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1; Ginsenoside-Rh1 | ||
| Ginsenoside Rh1 (Prosapogenin A2) inhibited the expression of PPAR-γ, TNF-α, IL-6 and IL-1β. | ||
| M5130 | Cisapride | 5-HT Receptor |
| R 51619; (±)-Cisaprid | ||
| Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent hERG potassium channel inhibitor. IC50 Value is 0.14 μM (EC50 for 5-HT4 receptor). | ||
| M14981 | Sapropterin dihydrochloride | Others |
| (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride | ||
| Sapropterin ((6R)-BH4) dihydrochloride is a synthetic form of BH4 that is approved for the treatment of BH4 responsive PKU. | ||
| M27801 | Saperconazole | Antifungal |
| R66905 | ||
| Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L. | ||
| M27815 | 3-Deoxysappanchalcone | Anti-infection |
| 3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC50 = 1.06 μM). | ||
| M38720 | 4-O-Methylsappanol | Antifungal |
| 4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana. 4-O-Methylsappanol (EC50 of 4.6 μM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells. | ||
| M38800 | β-Hederin | Parasite |
| β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively. | ||
| M38857 | Episappanol | TNF Receptor |
| Episappanol is a natural compound isolated from Caesalpinia sappan heartwood with anti-inflammatory activity. Episappanol significantly inhibits the IL-6 and TNF-α secretion. | ||
| M38943 | Caulophyllogenin | PPAR |
| Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation. | ||
| M38986 | Anemarsaponin B | NO Synthase |
| Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. | ||
| M39972 | Notoginsenoside T5 | Others |
| Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng. | ||
| M39983 | Pulchinenoside E2 | Others |
| Pulchinenoside E2 (Compound 8) is a triterpene saponin isolated from the roots of Pulsatilla chinensis. Pulchinenoside E2 shows cytotoxic to HL-60 cells with an IC50 value of 2.6 µg/mL. | ||
| M40202 | 11(α)-Methoxysaikosaponin F | Others |
| 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). | ||
| M45365 | Lobatoside C | Others |
| Lobatoside C, a triterpenoid saponin isolated from hyoscyamus with arabinose terminal sugar, inhibited SW-620, SK-MEL-5, and UO-31 cell lines with GI50 values of 8.91, 4.17, and 6.03, respectively. | ||
| M58415 | Cu(II)-Elesclomol | Cuproptosis |
| Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol. Cu(II)-Elesclomol induces cuproptosis. Cu(II)-Elesclomol also inducesapoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
