About 8 results found for searched term "S12" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3954 | Strontium ranelate | Calcium-sensing Receptor |
| SrR; S12911; Distrontium renelate | ||
| Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells. | ||
| M21697 | CMS-121 | Acetyl-CoA Carboxylase |
| CMS121 | ||
| CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC50 values of 7 nM and 200 nM, respectively. | ||
| M28576 | PS121912 | Vitamin |
| PS121912 is a selective vitamin D receptor (VDR)-coregulator inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer. | ||
| M51414 | Myristoyl-(Lys12, 27, 28)-VIP-Gly-Gly-Thr free acid | Others |
| Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) is a high-affinity and selective VPAC2 receptor antagonist. | ||
| M54264 | S12 | Others |
| S12 is a mutant RAS peptide containing the Gly (G) to Ser (S12) substitution. | ||
| M55252 | FS120 | TNF Receptor |
| FS-120 | ||
| FS120 is a first-in-class dual-agonist tetravalent bispecific antibody targeting CD137 (4-1BB, TNFRSF9) and OX40 (CD134, TNFRSF4). FS120 has the potential to show activity in "cold" tumors and improve outcomes of existing immunotherapies by simultaneously agonizing CD137 and OX40. | ||
| M56440 | DS12881479 | MNK |
| DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. | ||
| M59032 | SMS121 | Immunology/Inflammation |
| SMS121 is a novel CD36 inhibitor. SMS121 reduced the uptake of fatty acid into AML cells that could be reversed by addition of free fatty acids and caused decreased cell viability. | ||
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