About 1 result found for searched term "Ro 6842262" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28326 | Ro 6842262 | LPL Receptor |
| LPA1 receptor antagonist 1 | ||
| Ro 6842262 (LPA1 receptor antagonist 1) is an orally bioavailable, highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM. Ro 6842262 attenuates NHLF human lung fibroblast cell proliferation and contraction in vitro. Ro 6842262 also reduces plasma histamine levels in mouse LPA-challenge model. | ||
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