About 5 results found for searched term "RUNX-IN-2" (0.262 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41293 | RUNX-IN-2 | Apoptosis |
| RUNX-IN-2 covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. | ||
| M9498 | CADD522 | ROS |
| CADD522 is a novel small molecule inhibitor of RUNX2, downregulates RUNX2-mediated transcription of downstream target genes by inhibiting RUNX2-DNA binding, with an IC50 of 10 nM. | ||
| M28060 | AI-10-47 | Others |
| AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM. | ||
| M28317 | Ro24-7429 | HIV Protease |
| Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects. | ||
| M30817 | RUNX1/ETO tetramerization-IN-1 | Others |
| RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor of RUNX1/ETO tetramerization, exhibits anti-leukemic effect. RUNX1/ETO tetramerization-IN-1 specifically targets to NHR2 of RUNX1/ETO (EC50=0.25 μM), restores gene expression down-regulated by RUNX1/ETO. RUNX1/ETO tetramerization-IN-1 inhibits the proliferation of RUNX1/ETO-depending SKNO-1 cells, and reduces the RUNX1/ETO-related tumor growth in a mouse model. | ||
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