About 7 results found for searched term "RR-SRC" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M50407 | RR-SRC | Src-bcr-Abl |
| RR-SRC is a substrate for src-tyrosine-specific protein kinase. | ||
| M20763 | DGY-06-116 | Src-bcr-Abl |
| DGY-06-116 is an irreversible covalent and selective inhibitor of Src with IC50 of 2.6 nM. | ||
| M27767 | Pyridostatin | DNA/RNA Synthesis |
| RR82 | ||
| Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells. | ||
| M28071 | S116836 | Src-bcr-Abl |
| S116836, a potent, orally active BCR-ABL tyrosine kinase inhibitor, blocks both wild-type as well as T315I Bcr-Abl. S116836 arrests the cells in the G0/G1 phase of cell cycle, induces apoptosis, increases ROS production, and decreases GSH production in BaF3/WT and BaF3/T315I cells. S116836 also inhibits SRC, LYN, HCK, LCK and BLK, and receptor tyrosine kinases such as FLT3, TIE2, KIT, PDGFR-β. Antitumor activies. | ||
| M29235 | Squarunkin A | Src-bcr-Abl |
| Squarunkin A is a potent and selective UNC119-cargo interaction inhibitor, interrupting the UNC119A-myristoylated Src N-terminal peptide interaction (IC50=10 nM). Squarunkin A interferes with the activation of Src kinase in cells. | ||
| M29706 | DGY-06-116 | Src-bcr-Abl |
| DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM. | ||
| M54186 | pp60 c-src (521-533) (phosphorylated) | Others |
| pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
