About 1 result found for searched term "RMC-7977" (0.244 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54858 | RMC-7977 | Ras |
| RMC7977 | ||
| RMC-7977 is a highly selective, reversible, tri-complex RAS inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS, with affinity for both mutant and wild type (WT) variants. RMC-7977 demonstrated potent activity against RAS-addicted tumours carrying various RAS genotypes, particularly against cancer models with KRAS codon 12 mutations (KRASG12X). | ||
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