About 6 results found for searched term "RADA16" (0.152 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10196 | RADA16 | Peptides |
| RADA 16 | ||
| RADA16 | ||
| M5915 | Radafaxine HCl | Monoamine Oxidase |
| GW-353162A; BW-306U | ||
| Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. | ||
| M21150 | TMX-4116 | Casein Kinase |
| TMX-4116 is a casein kinase 1α (CK1α) degradation agent. tmx-4116 shows a preference for CK1α degradation in MOLT4, Jurkat and MM.1S cells with DC50 less than 200 nM. tmx-4116 can be used in the study of multiple myeloma. | ||
| M21151 | ZXH-1-161 | Ligand for E3 Ligase |
| ZXH-1-161 is a potent cereblon (CRBN) regulator with an IC50 of 39 μM in wild-type MM1.S cells. ZXH-1-161 has selective degradation activity against GSPT1. ZXH-1-161 can be used in the study of multiple myeloma. | ||
| M29585 | KB02-SLF | PROTAC |
| KB02-SLF is a PROTAC-based nuclear FKBP12 degrader (molecular glue). KB02-SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-SLF. | ||
| M29586 | KB02-JQ1 | PROTAC |
| KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader (molecular glue), but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1. | ||
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