About 1 result found for searched term "Pralnacasan" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10905 | Pralnacasan | Caspase |
| VX-740; HMR 3480 | ||
| Pralnacasan (VX-740) is a potent, selective, non-peptide inhibitor with an oral active interleukin 1β-convertase (ICE, caspase 1) inhibitor,Ki 1.4 nM. Pralnacasan inhibits pro-inflammatory cytokines IL-18, IL-1β, and IFN-γ. Pralnacasan has the potential to be used in the study of osteoarthritis and rheumatoid arthritis. | ||
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