About 3 results found for searched term "Pifithrin-α" (0.101 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2036 | Pifithrin-α | p53 |
| Pifithrin hydrobromide; PFTα hydrobromide | ||
| Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. | ||
| M30033 | p-nitro-Pifithrin-α | p53 |
| p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet . non-alcoholic fatty liver disease. | ||
| M58435 | Pifithrin-α, p-Nitro, Cyclic | p53 |
| PFN-α | ||
| Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue. | ||
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