Pifithrin-α - Search Results | AbMole BioScience

About 4 results found for searched term "Pifithrin-α" (0.125 seconds)

Cat.No.	Name	Target
M2036	Pifithrin-α	p53
	Pifithrin hydrobromide; PFTα hydrobromide
	Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis.
M30033	p-nitro-Pifithrin-α	p53
	p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet . non-alcoholic fatty liver disease.
M58435	Pifithrin-α, p-Nitro, Cyclic	p53
	PFN-α
	Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.
M8014	Pifithrin-β hydrobromide	p53
	PFT-β hydrobromide
	Pifithrin-β hydrobromide is a stabilized pifithrin-α analog as well as a specific p53 inhibitor with low cytotoxicity.