About 4 results found for searched term "Palbociclib" (0.312 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1806 | PD 0332991 HCL | CDK |
| Palbociclib HCl | ||
| PD-0332991 HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. | ||
| M2913 | Palbociclib Isethionate | CDK |
| PD 0332991 isethionate | ||
| Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 2/3. | ||
| M6167 | Palbociclib | CDK |
| PD 0332991 | ||
| Palbociclib is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases. | ||
| M13398 | BSJ-03-204 | PROTAC |
| BSJ-03-204 is a Cereblon ligand linked to THE CDK ligand PROTAC, which is an effective, selective cdK4/6 dual inhibitor based on Palbociclib. The IC50 of CDK4/D1 and CDK6/D1 were 26.9 nM and 10.4 nM, respectively. | ||
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