About 1 result found for searched term "PTC299 " (0.119 seconds)
Cat.No. | Name | Target |
---|---|---|
M28065 | PTC299 | VEGFR/PDGFR |
PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies. |
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